Research assistant in the Gregersen group at Department of Cellular and Molecular Medicine (ICMM)

We are looking for a highly motivated and dynamic research assistant for a 6-month period to investigate novel factors regulating transcription and co-transcriptional processing.

The project will be focused on understanding how Serine/Arginine (SR)-related and CTD-associated factors (SCAFs) interacting with RNA polymerase II influences transcription and co-transcriptional processing using CRISPR/Cas9 technologies combined with profiling of transcription using state-of-the-art RNA-seq approaches.

Our research
The Gregersen group focuses on various aspects of co-transcriptional regulation primarily mediated by RNA-binding proteins. We use a wide range of experimental approaches including cell biology, next-generation sequencing (RNA-seq, TTchem-seq, mNET-seq, ChIP-seq, CLIP etc.) as well as molecular biology techniques (western blots, immunoprecipitations, peptide pull-outs and proteomics) to decipher the molecular mechanisms of factors involved in co-transcriptional regulation and the composition of transcription complexes.

We are an interdisciplinary research team and located in modern laboratories in the Mærsk Tower at the Panum Institute as part of the Center for Gene Expression (CGEN) at the Institute of Cellular and Molecular Medicine (ICMM).

Your job
The role of the candidate will primarily be to perform experiments in the laboratory, analyse and interpret data, scientific publication, and undertake training, as well as attend scientific seminars.

Profile
Essential experience and skills:

• You have a master’s degree in biology, biochemistry, molecular biomedicine or similar
• You are experienced in molecular biology techniques, mammalian tissue culture and transcriptomics
• Curious mind-set with a strong interest in transcription
• Proficient communication skills and ability to work in teams
• Excellent English skills written and spoken.

Desirable experience and skills:

• Knowledge related to co-transcriptional processing and its regulation
• Experience with CRISPR/Cas9 genome editing
• Experience with RNA-seq analysis.

Key criteria for the assessment of applicants
Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project, e.g. Biology. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years).

Certified copy of original Master diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.

As a prerequisite for a Research assistant employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database.

Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science.

Place of employment
The place of employment is at the Department of Cellular and Molecular Medicine (ICMM), Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories with access to state-of-the-art facilities for cell engineering, next-generation sequencing, flow cytometry, and mass spectrometry.

Scientific environment
The Department of Cellular and Molecular Medicine (ICMM) offers an ambitious scientific environment, with many different nationalities represented. ICMM aims to produce research with high international impact focusing on the functional cell, its genetic components and molecular cellular mechanisms in a medical context. ICMM currently comprises five research programmes, three high profile Research Centers as well as a number of international research groups. The scientists at ICMM are involved in high quality research based undergraduate and graduate teaching programs at the University of Copenhagen.

Information about the department can be found at: https://icmm.ku.dk/english/.

Terms of employment
The position is a fixed-term position limited to a period of 6 months. The starting date is February 19th, 2025. The average weekly working hours are 37 hours per week.

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at DKK 32,998 / EUR 4,399 (April 2024 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Questions
For further information please contact Lea H. Gregersen by e-mail: [email protected].

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

• Motivated letter of application (max. one page).
• CV incl. education, work/research experience, language skills and other skills relevant for the position.
• A certified/signed copy of your Master of Science certificate.
• List of publications (if any).

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills, and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You find information about the recruitment process at: https://employment.ku.dk/faculty/recruitment-process/

The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The Faculty of Health and Medical Sciences comprises approximately 7,823 students, 1,886 PhD students and 5,100 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community.
The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Kontakt
Lea Haarup Gregersen
E-mail: [email protected]

Info
Ansøgningsfrist: 22-12-2024

Ansættelsesdato: 19-02-2025

Arbejdstid: Fuldtid

Afdeling/Sted: Department of Cellular and Molecular Medicine (ICMM)