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Principal Scientist, Molecular Modelling & Structural Biology

H. Lundbeck A/S



Are you ready to make an impact on antibody drug discovery campaigns and advance our in silico pipelines? We are seeking a skilled Computer-Aided Drug Discovery modeller to join our team.

Your new role

Your main responsibilities will be to drive Drug Discovery projects by identifying, developing, and delivering high quality modelling approaches and hypothesis for design in a timely manner. You will be directly involved in the drug discovery project teams, where you will proactively lead modelling by using innovative modelling approaches, including physics-, and ML/AI-based Structure prediction methods to prioritize and design antibodies. You will have a high impact on drug discovery campaigns by driving project strategies, from hit finding, lead optimization and drug candidate selection.

Your future team

The Molecular Modelling & Structural Biology team is working closely together with Medicinal Chemistry and Biotherapeutic Discovery. You will join a team of 6 scientists with different backgournds, all contributing with their expertise to build a dynamic team advancing Lundbeck’s Drug Discovery projects. We are responsible for all Modelling/Computer-Aided Drug Design and Structural Biology supporting modalities. We are fully integrated in the discovery process, working in multi-disciplinary chemistry or biologics projects from early-stage hit-finding, lead optimization, to candidate selection.

The position is based in Copenhagen, Denmark.

What you bring to the team

  • You are an experienced, collaborative, and communicative modeller with a proven history of impactful application of modelling techniques in Drug Discovery projects.
  • You have a PhD in Computational Structural Biology or related field and several years of experience in Pharmaceutical Industry, comprehensive knowledge and experience with most Computer-Aided Drug Discovery concepts and techniques, including ML/AI- and Physics-based Structure prediction using Rosetta, Schrodinger, and AlphaFold-like tools, MD simulations, and FEP.
  • You have extensive experience and knowledge of design and protein/antibody engineering, and solving antibody engineering related concepts, like humanization, immunogenicity, and developability.
  • You have good communication skills, and ability to work flexibly and collaboratively in cross-functional teams across the organization.

Our promise to you

Lundbeck offers an inspiring workplace and innovative culture, where our curiosity, accountability and adaptability enable us to transform lives. We want to go faster and further on addressing the big unmet needs of people living with brain disorders. We offer rewarding careers with a mix of exciting tasks and development opportunities that are balanced with initiatives focused on your well-being.

We need every brain in the game, and at Lundbeck, we are committed to building a workforce that is as diverse as the people we serve. Read more about our commitment at www.lundbeck.com/global/about-us/our-commitment/diversity-and-inclusion

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Apply now

Can you see yourself in this role? We want to hear from you. Does this sound like your dream job, but you’re not sure if you meet all the requirements? We still want to hear from you!

Upload your CV and include a few lines about your motivation for applying. We ask you not to include a photo or personal information that does not relate to your professional experience.

If you have questions, please contact Henrik Keränen, Senior Manager, HKER@lundbeck.com.

Applications must be received by May 2nd 2025.

Learn more about us at www.lundbeck.com, LinkedIn or Instagram (@h_lundbeck).

#EveryBrainInTheGame

This job ad is intended for individuals seeking a career opportunity with Lundbeck. We engage with recruitment and search firms where needed on the basis of a written agreement, and we do not accept unsolicited requests of any kind. If you work as a recruitment consultant, you are kindly instructed to refrain from contacting Lundbeck or the hiring manager directly with suggested candidates. If you violate this policy, you do so at your own risk and for your own account, and Lundbeck will not assume any liability nor pay any associated fees resulting from such violation.

About Lundbeck
At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us.

Through cutting edge science and strong partnerships, we develop and market some of the world’s leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology.

The brain health challenge is real. Our commitment is real. Our impact is real.

About Lundbeck
At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us.

Through cutting edge science and strong partnerships, we develop and market some of the world’s leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology.

The brain health challenge is real. Our commitment is real. Our impact is real.

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Last chance to apply today! (02 May 2025)
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H. Lundbeck A/S

Main office: Ottiliavej 9, 2500 Valby

Lundbeck er en global medicinalvirksomhed, der er dybt engageret i at forbedre livskvaliteten for mennesker, der lever med psykiatriske og neurologiske lidelser. Til dette formål beskæftiger Lundbeck sig med forskning, udvikling, fremstilling, markedsføring og salg af lægemidler i hele verden. Virksomhedens produkter er målrettet sygdommesområderne inden for psykiatri og neurologi.

We DO NOT ACCEPT unsolicited job applications.
We perodically offer student internships

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