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Biomarker Expert

Novo Nordisk A/S

Category: Research Location: Måløv, Capital Region of Denmark, DK

About the department
Translational Science is a department in Global Diabetes, Cardio-renal and Translational research, Novo Nordisk A/S. As part of Novo Nordisk’s new strategy within chronic diseases, this department has a focus towards all translational aspects from human target validation to biomarker identification and precision medicine hypothesis generation in support of new treatments within Diabetes, Obesity, Cardiorenal (CR) & Liver Disease (LD) areas. Currently, the department consists of 10 employees dedicated to conceive, characterise and apply translational research integrating biomarker identification and patient stratification needs into each single experimental project.

Our commitment is to build a presence within diabetes, obesity, cardiovascular, kidney and liver disease research and to build a pipeline of differentiated candidate drugs in diabetes, obesity, heart failure, atherosclerosis, chronic kidney disease and non-alcoholic steatohepatitis.

The position
The Biomarker Expert is accountable for the translational and precision medicine strategy setup and execution in support of the Diabetes, Obesity, CR & LD portfolio. A key element of the strategy is human disease understanding, the delivery of a patient-focused portfolio and the build-up of a solid package of clinical biomarkers and patient selection strategies trough the access of clinical cohorts.

You will become the scientific and strategic driver responsible for generating biomarker data, setting up and executing patient-centric translational strategies for Diabetes, Obesity, CR & LD projects from target ID until human PoC studies and beyond. An essential part of this is implementing high quality actionable biomarker plans aiming at discovery of measurable target engagement, drug-response pharmacodynamic biomarkers and patient selection/stratification hypothesis.

In addition to this you will assume responsibility for uncovering the biology and mechanisms causing human Diabetes, Obesity, CR & LD. You will also be in charge of supporting the design, coordination and follow up of experimental medicine a/o external disease natural history studies aiming at human data generation. You will work in close collaboration with Global Drug Discovery scientists, Global Research Technology and the Translational Medicine research team to mine clinical, genomic and omics data from internal or external data collections to develop personalized healthcare strategies.

You hold a PhD and/or MD with a scientific background in at least one of the following areas: diabetes, diabetic complications, with a particular emphasis on cardiovascular/dyslipidaemia, chronic kidney or liver diseases. You have a minimum of 5 to 10 years of experience in leading translational cross-functional teams preferably in the pharmaceutical industry.

We are looking for a candidate with these qualifications:

  • A set of skills combining clinical and preclinical understanding of the diabetes, obesity, cardiovascular/dyslipidaemia, kidney or liver diseases with sufficient exposure to basic research.
  • Track-record of discovery, set-up, development and delivery of biomarkers assays for clinical and research use, for pharmacodynamic, drug-response monitoring and patient selection.
  • Practical experience with multi-dimensional omics data and clinical data with the focus of discovering disease-linked biomarkers of response and disease progression.
  • Sound understanding of early clinical development.
  • Experience in biomarkers and precision medicine strategy implementation and deployment during the drug development process.
  • Desire to impact a young and innovative portfolio of targeted programs from inception through life cycle management.
  • You foster innovation by applying forward and reverse translation. The emphasis is how real-time human clinical data may directly inform new discoveries of targets or identify patients responding better to therapies.
  • You are a skilled communicator with strong influencing competencies. You have a strong motivation to have an impact in the organization.
  • You have experience setting up and driving scientific collaborations with internal and external stakeholders.
  • You are a dynamic self-starter capable of pro-actively leading and driving biomarker and Precision Medicine hypothesis.
  • You are a team-player, with ability to help and motivate colleagues around you.

Working at Novo Nordisk
The department is part of Global Drug Discovery, which specialises in the discovery of biological medicines for the treatment of diabetes, obesity, haemophilia, chronic liver disease, Chronic Kidney disease and cardiovascular diseases. We always strive for excellence and continuously develop our expertise to stay ahead - both as a company and as an individual. We believe that innovation and creativity thrive in a healthy and engaging working environment. Therefore, we give you the opportunity to bring your personal ambition and passion to work to improve the quality of life of the patients.

For more information, please contact Ivan Formentini by email: ivaf@novonordisk.com

Applications will be evaluated as they come in. Final deadline July 22, 2020

Millions rely on us
To work for Novo Nordisk you will need the skills, dedication and ambition to change lives for the better for millions of patients living with diabetes and other chronical diseases. In exchange, we offer the chance to be part of a truly global workplace, where passion and engagement are met with opportunities for professional and personal development.

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Ansøgningsfrist d. 22.07.2020
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Novo Nordisk A/S - hurtigt overblik

Novo Nordisk A/S
Novo Nordisk A/S
Novo Nordisk is a global healthcare company with more than 90 years of innovation and leadership in diabetes care. This heritage has given us experience and capabilities that also enable us to help people defeat other serious chronic conditions: haemophilia, growth disorders and obesity.

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