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We are strenghtening our pharmacometrics area, so this is a unique opportunity to join a dynamic biotech company in an exciting position.

The role
As our new pharmacometrician, you will contribute to the advancement of drug candidates across Ascendis Pharma’s portfolio. You will be part of a dedicated cross-functional team covering clinical and non-clinical R&D. You will work in multidisciplinary international project teams with key responsibility to design and perform modelling analyses to support decision making and submissions for drug projects. You will work across the matrix, both independently and in collaboration with other R&D members as well as external partners (CROs). You will have access to a platform with up-to-date modelling software allowing for state-of-the-art pharmacometric analyses.

Ascendis Pharma is a fast-growing, dynamic biopharmaceutical company with Headquarters in Denmark that offers you room to grow and the freedom to take responsibility and make a difference for patients every day. As a member of our global team, you will work with highly skilled and passionate colleagues to advance our exciting product pipeline.

Main areas of responsibility

  • Perform PK(PD) modelling analyses to support project decision making and contribute to regulatory filings
  • Cooperate closely with the pharmacometrics team to advance the pharmacometrics area in Ascendis Pharma
  • Assist project teams in design of programs and studies to encompass the modelling strategy
  • Liaise with Biometrics colleagues to enable generation of data sets for modelling analyses
  • Write modelling reports, sections of INDs/CTA/NDAs/MAAs etc. and publications
  • Maintain awareness of innovation and regulatory expectations in the modelling environment
  • Set up and maintain collaborative relationships with internal and external functional experts on assigned projects

Your professional qualifications
You hold a PhD (or equivalent) in a relevant biological/mathematical science and minimum 5 years of experience as a pharmacometrician/modeller working with NONMEM.

Furthermore you have
At least 2-5 years of industry experience in addition to technical expertise to organize and perform modelling analyses including:

  • Population PK(PD)
  • Extrapolation from nonclinical to clinical PK
  • Simulation of PK for new formulations
  • Extrapolation of PK to new populations including paediatrics

As a person, you are

  • A highly pro-active and analytical individual with a strong scientific background enjoying challenges and working in a friendly collaborative and quickly developing environment
  • Able to work in a structured way and have a high quality-oriented mindset with the right level of details, keeping the overall picture in mind
  • Possessing strong interpersonal skills as you will be collaborating with many different internal and external stakeholders
  • A strong communicator with a demonstrated ability to effectively present modelling analyses and make recommendations

Travel: 10-30 days per year.

Office location: Ascendis Pharma resides in a wonderful office facility in Tuborg Havn in Hellerup, north of Copenhagen, with a view to the harbour, the canals, and the sea.

For more details about the position or the company, please contact Director, Pharmacometrics Kristin Petri (+4530441043) or Sr. Director for Bioanalysis and PK/PD Britta Bysted (+4561615084) or visit out website www.ascendispharma.com. All applications must be submitted in English and are treated confidentially.

Applications will be evaluated when received, so please apply as soon as possible.


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ASCENDIS PHARMA A/S - hurtigt overblik

Ascendis Pharma is applying its innovative TransCon technologies to build a leading, fully integrated biopharmaceutical company focused on making a meaningful difference in patients’ lives. Guided by our core values of patients, science and passion, we utilize our technology platform to create new and potentially best-in-class therapies.

Tuborg Boulevard 5, 1.
2900 Hellerup
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