Research Assistant/PhD Position in Cancer Genetics at Rigshospitalet

Do you want to contribute to groundbreaking research with a direct impact on patients’ diagnosis and medical treatment?

The Department of Clinical Genetics at Rigshospitalet invites applications for a 1-year position as a Research Assistant in molecular genetics, with the possibility of transitioning into a 3-year PhD position. This exciting opportunity is offered in collaboration with Department of Clinical Genetics, Odense University Hospital and Biotech Research & Innovation Centre (BRIC), Copenhagen University. The successful candidate will be working across these institutions, however mainly in our laboratory in Glostrup or Copenhagen.

The position is available from May 1st, 2025, or as soon as possible thereafter.

Job Description
We are seeking a dedicated and talented researcher to join our team in developing novel functional and cell-based assays for interpreting germline variants (i.e. mutations) found in patients or healthy individuals to determine if they are cancer-causative or not. Using novel CRISPR/Cas9 technology, which you will take part in developing, and other molecular biological techniques, the research aims to improve the clinical diagnosis of genetic disorders, thereby influencing patient diagnosis, treatment options, and predictive family testing.

As a Research Assistant, you will work closely with our interdisciplinary team to plan a PhD project, preparing for a subsequent funded PhD position.

We Offer:

• Scientifically challenging research with direct clinical relevance
• Collaboration with specialists across different fields
• Strong mentorship from supervisors and researchers at Rigshospitalet, Odense University Hospital, and BRIC
• Access to advanced research training in a rapidly developing field at leading institutions

Qualifications and Expectations
The ideal candidate:

• Holds a Master’s degree in science or engineering
• Specializes in biomedicine, molecular biology, biochemistry, or a related field
• Has experience (preferably) in:
  • Mammalian cell culture
  • Germline variant analysis
  • CRISPR-Cas9 gene editing
  • Cell biology, molecular biology, and biochemistry
  • Cancer genetics og bioinformatics

Salary and Terms of Employment
Employment will be in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations).

This is a 1-year position with the intention of transitioning into a 3-year PhD fellowship.

Application Process
The application must be written in English and submitted as a PDF or .docx file, including:

• Cover letter (describing relevant expertise and motivation)
• Curriculum Vitae (CV)
• Academic certificates (including Master’s degree diploma)
• Optional: Letter(s) of recommendation

Incomplete applications will not be considered. Shortlisted candidates may be invited for an interview, and references will be obtained for the top candidate from their most recent and previous employers as necessary.

We will review applications and invite candidates for interviews on a continuous basis, so we encourage interested applicants to submit their applications as soon as possible. Deadline for application is April 18th, 2025.

Contact Information
For further details about the position, please contact:

• Professor Thomas v. O. Hansen, Department of Clinical Genetics, Rigshospitalet, Thomas.Van.Overeem.Hansen@regionh.dk, tlf. 26836044
• Molecular Biologist, PhD Jane Hübertz Frederiksen, Department of Clinical Genetics, Rigshospitalet, Jane.huebertz.frederiksen@regionh.dk, tlf. 29204860
• Professor Thomas v. O. Hansen, Department of Clinical Genetics, Rigshospitalet, Thomas.Van.Overeem.Hansen@regionh.dk, tlf. 26836044
• Professor Mads Thomassen, Department of Clinical Genetics, Odense University Hospital, mads.thomassen@rsyd.dk, tlf. 65412839
• Associate professor and group leader Morten Frödin, BRIC, University of Copenhagen. morten.frodin@bric.ku.dk, tlf. 35325654

About the Department of Clinical Genetics
The Department of Clinical Genetics at Rigshospitalet provides diagnosis, management, and counseling for patients and families with chromosomal anomalies, inherited metabolic disorders, and genetic conditions. The department operates specialized clinics and laboratories.

Our approach integrates cutting-edge genetic analyses with personalized, non-directive genetic counseling, ensuring the best possible care for individuals and families.

We look forward to receiving your application

Department:

Lokation: Rigshospitalet - Blegdamsvej

Application deadline: 18 Apr 2025