Technician for Analytical Characterization laboratory

Technician for Analytical Characterization laboratory We are looking for a technician in a 2-year position to join the Analytical Characterization team within the Analytical Development department. The position as technician with focus on biochemical characterization offers a unique opportunity to take part in the development of Symphogen antibody products from early research and throughout late-stage CMC development.
In the Analytical Characterization team, employed by 4 scientists and 4 technicians, we are responsible for analytical support to the research area during their lead selection process, and for further characterization studies during the CMC development phase to support e.g. cell line generation, drug substance process development, formulation development, In-use/compatibility as well as conducting comparability studies. In addition, the team is responsible for two laboratories, the Biophysical characterization laboratory and the Mass spectrometry laboratory, the latter in which this position is located. The MS laboratory is equipped with a high-end mass spectrometry platform based on the Orbitrap technology e.g. Ascend and Exploris. The MS platforme is coupled to most separation techniques (liquid chromatography and capillary electrophoresis (ZipChip)) and is using state-of-the-art Protein Metrics software (Byosphere Enterprise) for MS data mining.

As an ideal candidate you have experience with running High Performance liquid chromatography (HPLC) and Mass spectrometry analysis of proteins on both the intact and peptide level. Additionally, experience with several of the following analytical techniques would be Preferred: Capillary electrophoresis (CE-SDS) or imaging capillary isoelectric focusing (iCIEF), concentration determination (SoloVPE), dynamic light scattering (DLS), subvisible particle measurements (MFI and FlowCam), viscosity (Initium One) and, nano-differential scanning fluorimetry (Prometheus).

As a person you are self-driven, motivated, flexible and can execute tasks independently. You thrive with challenges and by working in a fast-paced environment with diverse tasks and opportunities for development. You will be joining a highly motivated team with supportive and helpful colleagues and a good collaborative spirit where we like to go the extra mile to support the projects and each other.
Required Qualifications

• Relevant education as technician (Laborant, Bioanalytiker) or equivalent
• Experience with biochemical characterization
• Experience with HPLC and MS analysis incl data evaluation of proteins, preferably antibodies
• Self-driven, highly motivated team player with commitment, initiative and humor

Preferred Qualification

• Experience with biophysical and/or general testing techniques for proteins, e.g. concentration, CE-SDS/iCIEF, subvisible particles, NanoDSF, DLS etc.
• Experience with developability assessment of antibodies
• Experience with Chromeleon
• Language skills: written and verbal (English)

We offer

• A challenging and versatile job in an innovative, focused and committed biotech environment
• Competitive salary based on qualifications, and flexible working hours
• Strong cross functional teamwork, room for individual performance and development, and passionate, inspiring, and fun colleagues

Working in Symphogen
Being part of Symphogen, you will have a challenging job in a creative, goal-oriented, and value-based environment with a meaningful mission: to advance superior monoclonal antibody therapeutics to improve the lives of patients. You will be a part of a highly engaged and inspiring organization with a focus on diversity, teamwork, commitment – and on you as a person. You will be offered good development opportunities and a relevant benefit package.
For further information
For more information you are welcome to contact Mette Pinstrup Jensen, Director Analytical Development at +45 30100448 ([email protected]) or HR-Manager, Pia Holm Olesen at +45 45265050. Please also see www.symphogen.com for information about our company.

If you are interested in the position, please mark your application and CV “Technician, Analytical development” and mail it to: [email protected] no later than December 22, 2024. Potential candidates will be invited for interview as they apply, and we reserve the right to terminate before the posting expires. Applications in both English and Danish are accepted.

We look forward to hearing from you!

Company
Symphogen is a subsidiary of Servier and antibody center of excellence primarily focused on oncology and immune oncology. We have a highly efficient antibody discovery and research platform supported by comprehensive early development capabilities.

Our antibody platform delivers antibodies with unique functionalities providing best or first in class potential as combination or mono therapy. Our approach and capabilities are well suited for combination therapies at the core of future cancer treatment.

Symphogen is located in Ballerup in the greater Copenhagen area. The company currently employs approximately 150 people

We aim to attract employees who can challenge status quo in the pursuit of excellence