Postdoc on adipose microvascular dysfunction in obesity

Application deadline: 15 June 2024 at 23:59 hours local Danish time
Three year Novo Nordic Foundation funded Postdoc on adipose microvascular dysfunction in obesity

Are you curious to understand, and therapeutically target, gene circuits regulated by obesity-associated microRNAs in adipocytes and adipose endothelial cells in living mice?

Would you like to receive hands-on training and apply multimodal -OMICS like m(i)RNA Sequencing, utilize proprietary AAV vectors for perturbing miRNA function in selected cell types in obese mice, use computational approaches to predict microRNA-mRNA gene networks in these diseased cell types, and have access to novel transgenic mice for studying cellular crosstalk by secreted microRNAs?

A position as postdoctoral fellow is available at the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, with a flexible starting date (1st of July 2024 being the earliest time point possible). The position is initially funded for three years by the Novo Nordisk Foundation (NNF), with the possibility of extension. Beyond this project, you will get the chance to interact with the NNF-funded Center for Adipocyte Signaling (www.sdu.dk/en/adiposign) which has undertaking a holistic approach to understand adipocyte dysfunction using multimodal gene profiling in obese patients and rodent models.

The employee will be part of Jan-Wilhelm Kornfeld’s research group (www.kornfeldlab.com) that is interested in dissecting the function, and therapeutic potential, of obesity-associated microRNAs in adipose cell types such as adipocytes and adipose endothelial cells.

We are seeking an enthusiastic new colleague with a PhD degree in life sciences (biologist, biochemist, biomedical degree or related) with one or many of the following skills:

• • (micro)RNA Sequencing and/or single-cell resolved NGS approaches.
• • Computational prediction of disease-associated miRNA-mRNA gene networks.
• • Deep knowledge in adipose tissue biology and its dysfunction during obesity.
• • Maintenance and metabolic phenotyping of transgenic mice.
• • Assisting in grant funding applications, training of students and guests.

You excel by the following education and background:

• • A PhD degree in life sciences with focus on miRNA, physiology, biochemistry or exosome biology.
• • First authorship in a leading journal in the field.
• • Proficiency in R and/or one of the main scripting languages (e.g. Python) and/or the willingness to receive training in computational analyse of (micro)RNA Seq from humans and mice.
• • Good collaborative skills, a positive attitude towards science and its contribution to society.
• • Diligence and intellectual flexibility as required for an academic position.
• • An open and positive mind that actively contributes to the infrastructure and the success of the research team.

Application deadline: 15 June 2024 at 23:59 hours local Danish time
Further information can be obtained from Professor Jan-Wilhelm Kornfeld’s email: [email protected], phone +45 9350 7481.

Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.

The application must include the following:

• A curriculum vitae including information on previous employment
• A full list of publications stating the scientific publications on which the applicant wishes to rely
• Copy of PhD diploma

Shortlisting may be used in the assessment process.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated.

To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Applications must be submitted electronically using the link "Apply now". Attached files must be in Adobe PDF format. We strongly recommend that you read How to apply for a position at SDU before you apply.

Further information for international applicants about entering and working in Denmark.

Placering: Odense, Denmark