Postdoc in Hyperspectral Raman Imaging - DTU Health Tech

Join the 4DMAPPER project to develop a label-free molecular profiler for 4D mapping of transport and metabolism in ex-vivo tissue. Design optical instrumentation, build a Raman microscope, and fabricate metasurface microlens arrays. Required: experience in Raman spectroscopy, optical metasurfaces, or micro/nano-fabrication.
Are you passionate about optical metasurfaces and biosensors, with interest in pushing the boundaries for detection of mass transport and metabolism in tissue by hyperspectral Raman Imaging, you may be our new post-doc.

With the project 4DMAPPER - 4D mapping of transport and metabolism in organ on a chip, we develop a novel, label-free dynamic molecular profiler with high resolution in space and time (4D). 4DMAPPER will enable localized measurements of unlabeled molecules in 3D, and real-time visualization of mass transport in ex-vivo tissue and other 3D materials.

Responsibilities and qualifications
We are seeking a highly motivated Postdoctoral Researcher to join our dynamic team. Your will be responsible for the design, building and validation novel optical instrumentation for hyperspectral Raman Imaging of ex-vivo tissue. In addition to building a dedicated Raman microscope in the optofluidics lab at DTU Health Tech, you will be responsible for the design and fabrication of optical metasurface microlens arrays optimized for hyperspectral Raman Imaging. You will fabricate metasurface microlens arrays at the DTU Nanolab cleanroom facility. You will work in close collaboration with a fellow post-doc at the department, who develops customized trans-well lab-ware with ex-vivo tissue samples for the project.

Your primary tasks will be:

• Build and optimize Raman hyperspectral imaging setup based on existing prototype, with single focal spot illumination and z-scan.
• Design and fabricate customized microlens arrays, optimized for hyperspectral Raman Imaging: High numerical aperture and low chromatic aberrations.
• Integrate fabricated microlens arrays in setup for high resolution 4D (time and space) hyperspectral Raman imaging without moving parts.
• Validate and optimize hyperspectral Raman Imaging setup to measure transport over gel- and cell barriers (in collaboration with fellow post-doc).

We expect that you have documented experience in experimental physics within minimum two of the following three fields: (i) Raman spectroscopy, (ii) optical metasurfaces, (iii) micro/nano-fabrication.

As a formal qualification, you must hold a PhD degree (or equivalent).

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 2 years. Stating date is 1 January 2025 (or according to mutual agreement). The position is a full-time position.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Professor Anders Kristensen, [email protected].

You can read more about DTU Health Tech at www.healthtech.dtu.dk.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 4 December 2024 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• Application (cover letter)
• CV
• Academic Diplomas (MSc/PhD – in English)
• List of publications

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position.

DTU Health Tech
With a vision to improve health and quality of life through technology, DTU Health Tech engages in research, education, and innovation based on technical and natural science. We educate tomorrow’s health tech engineers and create the foundation for new and innovative services and technologies for the globally expanding healthcare sector with its demands for the most advanced technological solutions. DTU Health Tech’s expertise can be described through five overall research areas: Diagnostic Imaging, Digital Health, Personalised Therapy, Precision Diagnostics, and Sensory and Neural Technology. Our technologies and solutions are developed with the aim of benefiting people and creating value for society. The department has a scientific staff of about 210 persons, 140 PhD Students, and a technical/administrative support staff of about 100 persons of which a large majority contributes to our research infrastructure and related commercial activities.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

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