Senior Mass Spectrometry Specialist

Department of Clinical Biochemistry, Bispebjerg Hospital

Are you motivated by improving clinical diagnostics through advanced mass spectrometry and proteomic technologies? We are looking for a Senior Mass Spectrometry Specialist to join the Department of Clinical Biochemistry at Bispebjerg Hospital. You will play a key role in strengthening our LC-MS/MS capabilities and driving innovation at the interface of clinical chemistry, proteomics, and translational research.

This is a 3-year full-time position starting 1. January 2026 (or by agreement), with the possibility of extension. Your will work in Professor Nicolai J. Wewer Albrechtsen’s research group, and in the clinical LC-MS/MS section, and be part of a dynamic clinical proteomics team dedicated to developing next-generation diagnostic tools.

Your Responsibilities

• Lead the development, optimization, and implementation of LC-MS/MS workflows, including DIA, DDA, PRM, and targeted assays.
• Ensure reliable and high-quality performance of LC-MS/MS instruments through method development, routine QC, troubleshooting, and coordination with external vendors.
• Oversee instrument qualification, service, and maintenance, ensuring minimal downtime in a clinical laboratory setting.
• Drive laboratory innovation by evaluating, validating, and integrating new separation technologies and automation solutions.
• Provide senior technical guidance and supervision to bioanalysts, researchers, and students in sample preparation, data acquisition, and workflow execution.
• Collaborate with clinicians, chemists, pathologists, and bioinformaticians to translate proteomics data into clinically meaningful insights.
• Lead LC and LC-MS–based method development for comprehensive characterization of proteins, peptides, and biologics.
• Ensure compliance with hospital quality systems, maintaining high standards of documentation, data integrity, and traceability.
• Present results, progress, and methodological updates in departmental, interdisciplinary, and cross-functional meetings.
• Foster a collaborative, service-oriented, and patient-focused laboratory culture, supporting continuous improvement and knowledge sharing.
  

What We Expect

• Hold a degree in proteomics, analytical chemistry, biomedicine, bioengineering, or a related field (PhD or equivalent experience preferred).
• Have substantial hands-on experience with LC-MS/MS method development and maintenance.
• Bring strong expertise in MS-based proteomics (DIA, DDA, PRM).
• Have experience with data processing, QC, and visualization; Python or R is an advantage.
• Communicate clearly across disciplines and enjoy working in a clinical setting.
• Work independently with strong attention to detail.
• Preferably have experience with hospital workflows or regulated laboratory environments.
  

We Offer

• A central role in shaping the future of clinical proteomics at Bispebjerg Hospital.
• A dynamic interdisciplinary environment of clinicians, bioanalysts, researchers, and students.
• Opportunities for professional development and scientific collaboration.
• Access to modern LC-MS/MS platforms and state-of-the-art facilities.
• Engagement in a strong RegionH research network.
  

About the Department
The Department of Clinical Biochemistry provides 24/7 diagnostic services to Bispebjerg and Frederiksberg Hospitals and primary and specialist healthcare providers. The department handles more than 10.5 million tests annually and operates in modern facilities established in 2020. With around 140 staff members, including 80 bioanalysts, we value teamwork, innovation, and knowledge-sharing.

Contact & Application
For further information, please contact:

• Annelaura Bach Nielsen, Senior Data Analyst – [email protected]
• Prof. Nicolai J. Wewer Albrechtsen – [email protected]

Working hours: Full-time (37 hours/week)
Salary: According to the applicable collective agreement
Application deadline: 14. december 2025
Interviews will be conducted continuously during the application period.

Join us and contribute to the future of clinical diagnostics through advanced mass spectrometry.

Application deadline: Apply no later than 14. December 2025

Lokation: Bispebjerg og Frederiksberg hospital